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Handling non-ignorable dropouts in longitudinal data: A conditional model based on a latent Markov heterogeneity structure

机译:处理纵向数据中不可忽略的辍学:有条件的   基于潜在markov异质性结构的模型

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摘要

We illustrate a class of conditional models for the analysis of longitudinaldata suffering attrition in random effects models framework, where thesubject-specific random effects are assumed to be discrete and to follow atime-dependent latent process. The latent process accounts for unobservedheterogeneity and correlation between individuals in a dynamic fashion, and fordependence between the observed process and the missing data mechanism. Ofparticular interest is the case where the missing mechanism is non-ignorable.To deal with the topic we introduce a conditional to dropout model. A shapechange in the random effects distribution is considered by directly modelingthe effect of the missing data process on the evolution of the latentstructure. To estimate the resulting model, we rely on the conditional maximumlikelihood approach and for this aim we outline an EM algorithm. The proposalis illustrated via simulations and then applied on a dataset concerning skincancers. Comparisons with other well-established methods are provided as well.
机译:我们举例说明了一类条件模型,用于在随机效应模型框架中分析遭受磨损的纵向数据,其中假设特定于对象的随机效应是离散的,并遵循与时间有关的潜在过程。潜在过程以动态的方式解释了个体之间的不可观测性和相关性,以及所观察到的过程与缺失数据机制之间的依赖性。特别令人关注的是缺失机制不可忽略的情况。为了解决这一问题,我们引入了条件到辍学模型。通过直接建模缺失数据过程对潜在结构演化的影响,可以考虑随机效应分布中的形状变化。为了估计结果模型,我们依靠条件最大似然法,为此目的,我们概述了一个EM算法。该提案通过模拟进行了说明,然后应用于有关皮肤癌的数据集。还提供了与其他公认方法的比较。

著录项

  • 作者

    Maruotti, Antonello;

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  • 年度 2014
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  • 原文格式 PDF
  • 正文语种 {"code":"en","name":"English","id":9}
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